What is the research dosage of kisspeptin-10?

Human studies gave it as a single intravenous bolus expressed per kilogram of bodyweight — an LH response was observed from doses as low as around 0.3 nmol/kg, with study ranges reported up to roughly 10 nmol/kg (on the order of a few to ~13 mcg/kg). The distinctive feature is the per-kilogram bolus unit. These figures are reproduced strictly as a laboratory research reference and are not a human dosing protocol or medical advice.

What is kisspeptin-10's half-life?

Comparative work reports a plasma half-life of about 4 minutes for kisspeptin-10, versus roughly 32 minutes for the longer kisspeptin-54. That very short clearance is why KP-10 is used as a single bolus with a tight sampling window rather than a maintained infusion or a scheduled compound.

Why is kisspeptin-10 dosed as a single bolus instead of a schedule?

Because its half-life is only about 4 minutes. The research interest is an acute, measurable hormone response, so studies use a single per-kilogram bolus and a tight sampling window rather than a maintained infusion or a weekly amount — the compound is present only briefly.

Does Titan sell kisspeptin-10?

No. Titan does not stock kisspeptin-10. This page is an informational dosing reference and an honest pointer to Titan's in-house-tested research peptides. Nothing here claims a fertility or hormonal outcome — kisspeptin-10 is an investigational research compound.

Kisspeptin-10 · KP-10 decapeptide · research use only

Kisspeptin-10 is dosed per kilogram as a single bolus — because it's gone in about four minutes.

Kisspeptin-10 (KP-10) is the C-terminal decapeptide fragment of kisspeptin, the neuropeptide that sits upstream of GnRH. Its research dosing is unlike almost everything else in this catalog: human studies gave it as a single intravenous bolus expressed per kilogram of bodyweight, in nanomole-per-kilogram terms, because the study interest is an acute, measurable hormone response — not a maintained level. This page reproduces the per-kg bolus figures reported in the literature and the very short ~4-minute half-life that drives that single-bolus design, and explains why KP-10 is dosed differently from the longer KP-54. Framed as a research reference, not a human protocol. Titan does not stock kisspeptin-10; see the honest catalog pointer below.

Where to buy kisspeptin-10 — sourcing & COA In-house-tested research peptides

Per-kg IV bolus, in nmol/kg

Human studies dosed kisspeptin-10 as a single intravenous bolus expressed per kilogram — an LH response was observed from doses as low as ~0.3 nmol/kg, with study ranges reported up to ~10 nmol/kg (on the order of a few to ~13 mcg/kg). The distinctive part is the unit: a per-kilogram bolus for an acute measurement, not a fixed weekly amount. Reproduced strictly as a laboratory research reference, not a human instruction.

Sourcing and COA notes →

~4-minute half-life

Comparative work reports a plasma half-life of roughly 4 minutes for KP-10, versus about 32 minutes for the longer KP-54. Four minutes is why it is a single-bolus tool: the compound triggers a rapid, dose-dependent LH rise and clears almost immediately, so studies designed around it use a bolus and a tight sampling window rather than a maintained infusion or a weekly schedule.

Reference framing →

KP-10 vs KP-54: dosing follows the clock

KP-10 is the 10-residue C-terminal fragment; KP-54 is the longer 54-residue form. Their half-lives differ roughly eightfold (~4 vs ~32 minutes), and study designs compensate for that gap — which is exactly why a dosing figure for one does not transfer to the other. If a protocol is choosing between them, fragment length and the resulting half-life are the deciding variables.

Fragment length matters →

Per-kg bolus math

Because the reference is per-kilogram, the working amount depends on the subject mass in the model. As a worked example, a 1 mg vial in 1 mL bacteriostatic water gives 1 mg/mL; at ~10 nmol/kg (KP-10 ≈ 1302 Da, so ~13 mcg/kg) a 70 kg reference works out near ~0.9 mg per bolus. Confirm the vial's stated mass and the molecular weight before running any in-vitro model rather than assuming a fixed volume.

Run the numbers →

Verify the decapeptide sequence

Kisspeptin-10 is a defined 10-residue peptide, so a meaningful certificate confirms that exact sequence by mass spectrometry alongside an HPLC main-peak purity against a stated target. A truncated fragment can post a clean purity number while being the wrong molecule — and because activity is C-terminus-driven, identity of the full decapeptide is what matters, not the purity figure alone.

How to read a COA →

Research-use framing

These figures describe doses used in kisspeptin-10 research, reproduced strictly as a laboratory reference for in-vitro and modelling work — not instructions for human use. Kisspeptin-10 is an investigational compound; Titan does not sell it and supplies only research-use-only reagents, not for human or animal consumption. Nothing here is medical or dosing advice, and no fertility or hormonal outcome is claimed.

Research-use policy →

The detail, in plain terms

The kisspeptin-10 reference, in one table.

KP-10's dosing is a per-kilogram acute bolus, defined by its very short half-life. These are the variables a researcher weighs when modelling it — reproduced as a reference, not a human protocol. Titan does not stock kisspeptin-10.

Compound: Kisspeptin-10 (KP-10) — the 10-residue C-terminal fragment of kisspeptin.
Research dose: Single IV bolus, per-kg: LH response from ~0.3 nmol/kg, study ranges up to ~10 nmol/kg.
Route: Intravenous bolus in human studies (acute measurement, not maintained).
Half-life: ≈4 minutes (vs ≈32 minutes for the longer KP-54).
Reconstitution: 1 mg vial + 1 mL BAC water → 1 mg/mL; per-kg dosing scales with subject mass.
COA focus: Confirm the exact 10-residue sequence by MS — C-terminus drives activity.
Titan catalog: Not stocked. Honest pointer: Titan's in-house-tested research peptides.

Questions researchers ask

Before you order.

What is the research dosage of kisspeptin-10?: Human studies gave it as a single intravenous bolus expressed per kilogram of bodyweight — an LH response was observed from doses as low as around 0.3 nmol/kg, with study ranges reported up to roughly 10 nmol/kg (on the order of a few to ~13 mcg/kg). The distinctive feature is the per-kilogram bolus unit. These figures are reproduced strictly as a laboratory research reference and are not a human dosing protocol or medical advice.
What is kisspeptin-10's half-life?: Comparative work reports a plasma half-life of about 4 minutes for kisspeptin-10, versus roughly 32 minutes for the longer kisspeptin-54. That very short clearance is why KP-10 is used as a single bolus with a tight sampling window rather than a maintained infusion or a scheduled compound.
How is kisspeptin-10 different from kisspeptin-54?: KP-10 is the 10-residue C-terminal fragment; KP-54 is the longer 54-residue form. Their half-lives differ roughly eightfold (~4 vs ~32 minutes), and study designs compensate for that gap — so a dosing figure for one does not transfer to the other. Fragment length and the resulting half-life are the deciding variables.
Why is kisspeptin-10 dosed as a single bolus instead of a schedule?: Because its half-life is only about 4 minutes. The research interest is an acute, measurable hormone response, so studies use a single per-kilogram bolus and a tight sampling window rather than a maintained infusion or a weekly amount — the compound is present only briefly.
Does Titan sell kisspeptin-10?: No. Titan does not stock kisspeptin-10. This page is an informational dosing reference and an honest pointer to Titan's in-house-tested research peptides. Nothing here claims a fertility or hormonal outcome — kisspeptin-10 is an investigational research compound.