Semax · nasal spray · research use only
Semax dosage, framed for intranasal research.
Semax is a synthetic ACTH(4-10) heptapeptide studied for cognition and neuroplasticity, and it is sourced very differently from the injectable peptides most labs handle. In the research literature it is delivered intranasally, referenced in micrograms per administration rather than milligrams, and given acutely around a cognitive task instead of on a cumulative daily schedule. This page lays out the microgram framing, timing, and metered-spray delivery reported for Semax as a laboratory reference — not a human protocol or medical advice.
An ACTH(4-10) fragment, not a growth peptide
Semax is a short heptapeptide derived from the ACTH(4-10) sequence with a Pro-Gly-Pro tail added for stability. That origin is why it is studied for cognition and neuroplasticity rather than the recovery or metabolic questions that drive BPC-157 or the GLP-1 class — and why its dosing references read in micrograms rather than the milligram amounts used for injectable compounds.
Semax cognition research →Microgram ranges in the literature
Behavioural and neuroprotection research models intranasal Semax in microgram amounts per administration, with study designs spanning a wide single-dose window depending on the question. The defining feature is that it is an acute per-session amount delivered nasally, not a milligram daily total. These figures are a laboratory reference, not a human protocol.
Semax vs Selank framing →Short half-life, acute timing
Native Semax has a short systemic half-life; the Pro-Gly-Pro modification slows enzymatic breakdown relative to the bare fragment but it remains a short-acting peptide. Research designs therefore administer it acutely — a set interval before the cognitive task or measurement window — rather than relying on a standing accumulation. Timing relative to the experiment matters more than frequency.
Why timing matters →Metered spray — no reconstitution
Titan supplies Semax as a ready-to-use metered nasal spray, so there is no bacteriostatic-water reconstitution step like a lyophilized injectable vial. Each actuation delivers a fixed volume, which is what lets a per-session microgram reference map onto a known per-spray amount. Storage and handling follow the nasal-spray shelf-life guidance rather than vial reconstitution math.
Nasal spray storage →Identity and concentration to confirm
For a nasal-spray format, the verification points are peptide identity and the labelled concentration per actuation. Titan's Semax is characterised by mass-spec identity and HPLC purity against a ≥99% internal target on a lot-matched release sheet — so the microgram references on this page map onto a known concentration rather than an assumed one.
See the testing workflow →Research-use framing
Semax in this format has no regulatory approval for human use in most jurisdictions. The microgram ranges and timing here are reproduced as a laboratory research reference for in-vitro and behavioural-modelling work — not instructions for human use. Titan supplies Semax strictly as a research reagent, and nothing on this page is medical or dosing advice.
Research-use policy →The detail, in plain terms
The intranasal dosing reference, in one table.
The variables a cognition-research protocol weighs for intranasal Semax — the peptide's origin, the microgram unit convention, the short half-life that drives acute timing, and the metered-spray delivery that removes reconstitution. Reproduced as a reference, not a human protocol.
- Compound
- Semax — synthetic ACTH(4-10) heptapeptide with a Pro-Gly-Pro tail.
- Unit convention
- Micrograms (mcg) per administration, not milligrams.
- Reference amount
- Acute per-session microgram amounts; study designs span a single-dose window.
- Timing
- Acute — administered a set interval before the task/measurement window.
- Half-life
- Short systemic half-life; Pro-Gly-Pro tail slows enzymatic breakdown.
- Format
- Ready-to-use metered nasal spray, $59.99 — no reconstitution.
Questions researchers ask
Before you order.
- What is the research dosage for intranasal Semax?
- Behavioural and neuroprotection research models intranasal Semax in microgram amounts per administration, with study designs spanning a single-dose window depending on the question. It is referenced as an acute per-session amount delivered nasally rather than a cumulative milligram daily total. These figures are a laboratory reference, not a human dosing protocol or medical advice.
- Why is Semax dosed in micrograms instead of milligrams?
- Semax is a short, potent heptapeptide derived from the ACTH(4-10) fragment, and the research literature references its intranasal administration in micrograms — far smaller amounts than the milligram doses used for injectable peptides like BPC-157 or TB-500. The microgram convention reflects the compound's potency and the small per-actuation volume of a nasal spray.
- Does Titan's Semax nasal spray need reconstitution?
- No. Titan supplies Semax as a ready-to-use metered nasal spray, so there is no bacteriostatic-water reconstitution step like an injectable lyophilized vial. Each actuation delivers a fixed volume, which is what makes per-session microgram references practical to apply. Storage follows the nasal-spray shelf-life guidance rather than vial reconstitution math.
- Why is Semax administered acutely rather than daily?
- Semax has a short systemic half-life — the Pro-Gly-Pro tail slows breakdown relative to the bare fragment but it remains short-acting — so research designs administer it acutely, a set interval before the cognitive task or measurement, rather than on a standing daily schedule. Timing relative to the experiment matters more than dosing frequency.
- Is Semax approved for human use in this format?
- No. Titan's Semax nasal spray has no regulatory approval for human use in most jurisdictions. Titan Peptide Lab supplies it strictly as a research-use-only reagent for in-vitro and behavioural-modelling laboratory work — not for human or animal consumption, and not for diagnostic, therapeutic, or preventative use.